@font-face {
    font-display: swap;
    font-family: Helvetica Neue LT Pro extend;
    font-style: normal;
    src: local("Helvetica-Neue"),url(../fonts/Linotype\ -\ HelveticaNeueLTPro-BlkEx.otf) format("opentype")
}
@font-face {
    font-display: swap;
    font-family: Helvetica Neue LT Pro light extend;
    font-style: normal;
    src: local("Helvetica-Neue"),url(../fonts/Helvetica\ Neue\ LT\ Pro\ 43\ Light\ Extended.otf) format("opentype")
}

html {
    height: 100%;
}

/* Variables */
:root {
    --color-black:       #111827;
    --color-white:       #fff;
    --color-gray:        #D6D6D6;
    --color-pink:       #E3469D;
    --color-pink-two:   #1f927c;
    --color-pink-three: #E3469D;
    --color-blue:        #eef3fa;
    --color-neutral-100: #FAFAFA; 
    --color-neutral-500: #494954;
    --color-neutral-700: #374151; 
    --color-neutral-900: #1b120c;
    --font-size-default: 18px;
    --font-family-default: "Inter", sans-serif;
    --line-height-default: 26px;
}

/* General */
body {
    font-family: var(--font-family-default);
    font-size: var(--font-size-default);
    line-height: var(--line-height-default);
    color: var(--color-neutral-700);
    font-weight: 400;
    font-style: normal;
    background-color: var(--color-white);
}

h1 {
    font-family: Helvetica Neue LT Pro extend;
    color: var(--color-pink);
    font-size: 60px;
    line-height: 65px;
    padding-top: 80px;
    font-weight: 700;
    margin-bottom: 10px;
    text-transform: uppercase;
}

span {
    font-weight: lighter;
}

h3 {
    color: var(--color-black);
    font-size: 30px;
    font-weight: bold;
    margin-bottom: 30px;
}

h4 {
    font-size: 22px;
    line-height: 30px;
    font-weight: bold;
    color: var(--color-black);
    margin-bottom: 30px;
}

h5 {
    color: var(--color-black);
    font-size: 18px;
    line-height: 26px;
    font-weight: bold;
    margin: 20px 0 30px;
}

p {
    font-size: 16px;
    margin-bottom: 30px;
}

a {
    transition: all .3s ease;
    text-decoration: none;
}

img {
    max-width: 100%;
    height: auto;
}

ul {
    margin: 0;
    padding: 0;
    list-style: none;
}

.pink {
    color: var(--color-pink-three);
}

.grid  {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 50px;
}

.small {
    font-size: 12px;
    line-height: 20px;
    text-align: left;
}

hr {
    color: #BABABA;
    border: solid 2px;
}

.bg-grey {
    background-color: var(--color-neutral-100);
}

/* banner */
.banner {
    position: relative;
    width: 100%;
    height: auto;
    padding: 50px 0 80px;
}
.banner::before {
    content: '';
    width: 100%;
    height: 100%;
    background-size: 1920px;
    background: url(../img/banner.jpg) top right / contain no-repeat;
    position: absolute;
    top: -30px;
    right: 0;
    z-index: -1;
}
.banner .text p {
    margin: 0;
}
.banner h3 {
    margin-top: 115px;
}

/*about*/
.about {
    align-items: start;
}
.text-list ul li {
    color: var(--color-neutral-500);
    line-height: 24px;
    position: relative;
    padding: 20px 50px;
    border-bottom: 1px dashed var(--color-gray);
    font-size: 16px;
}
.text-list ul li:first-child {
    border-top: 1px dashed var(--color-gray);
}           
.text-list ul li:before {
    content: '';
    position: absolute;
    width: 32px;
    height: 32px;
    background-size: 25px;
    background-repeat: no-repeat;
    left: 0;
    top: 60%;
    transform: translateY(-50%);
    background-image: url(../img/check.svg);
}
.text-list p:last-child {
    margin-top: 40px;
}
.about-image img {
    width: 100%;
}
/*end about*/ 

/*Section impact*/
.impact {
    padding: 50px 0;
}
.impact .grid {
    gap: 80px;
}
.impact p {
    max-width: 575px;
}
.impact .img {
    margin: auto;
    text-align: center;
}
/*end Section impact*/

/*Section prevalence*/
.prevalence {
    padding-bottom: 100px;
}
.prevalence .container h5 {
    margin-top: 80px;
}
.prevalence p.small {
    margin-top: 20px;
}
.prevalence .prevalence-row {
    display: grid;
    grid-template-columns: repeat(5, 1fr);
    gap: 20px;
    margin-top: 90px;
}
.box {
    padding: 60px 40px 20px 30px;
    background-color: #F8F8F8;
    border-radius: 20px;
}
.box span {
    font-family: var(--font-family-default);
    font-size: 40px;
    line-height: 40px;
    font-weight: bold;
    color: var(--color-pink);
}
.prevalence .prevalence-row .prevalence-item {
    position: relative;
}
.prevalence .prevalence-row .prevalence-item img, .risks .risks-item img {
    position: absolute;
    top: 0;
    transform: translateY(-50%);
    left: 30px;
}
.box p {
    min-height: 52px;
    margin-top: 10px;
}
/*end Section prevalence*/

/* Section risks*/
.risks {
    padding: 90px 0;
    position: relative;
}
.risks .grid {
    padding: 55px 0;
    gap: 90px;
}
.risks hr {
    position: absolute;
    width: 75%;
    left: 12%;
    top: 45%;
    transform: translateY(-50%);
}
.risks .grid .risks-item {
    position: relative;
    display: flex;
    justify-content: flex-end;
}
.risks .grid .risks-item:last-child {
    justify-content: flex-start;
}
.risks .grid .risks-item .box {
    max-width: 400px;
    padding: 120px 75px 50px;
    background-color: var(--color-white);
    text-align: center;
}
.risks .grid .risks-item img {
    transform: translateX(-50%);
    left: 66%;
    top: -55px;
}
.risks .grid .risks-item:last-child img {
    left: 33%;
}
/*end Section risks*/

/*Section quality*/
.quality {
    padding-top: 100px;
}
.quality .grid {
    gap: 20px;
}
.quality .quality-text {
    max-width: 560px;
}
.quality .grid .quality-image img {
    width: 100%;
}
/*end Section quality*/
/*Section warnings*/
.warnings {
    padding: 30px 0 70px;
}
.warnings .box {
    margin: 20px 0;
    background-color: #f8f8f8;
    padding: 32px 20px;
    gap: 20px;
    border-radius: 8px;
    position: relative;
}
.warnings .box p {
    margin: 0 40px;
    color: var(--color-neutral-900);
}
.warnings .box p:before {
    content: '';
    position: absolute;
    width: 32px;
    height: 32px;
    background-size: 25px;
    background-repeat: no-repeat;
    left: 20px;
    top: 50px;
    transform: translateY(-50%);
    background-image: url(../img/exclamacao.svg);
}
.warnings .box img {
    margin-top: 5px;
}
/*end Section warnings*/

/*Section signals*/
.signals {
    padding: 100px 0 80px;
}
.signals .grid {
    gap: 70px;
    align-items: center;
}
.signals .text-list ul li:before {
    background-image: url(../img/exclamacao.svg);
}
/*end Section signals*/

/*Section factors*/
.factors {
    padding: 90px 0 100px;
}
.factors .text-list ul li {
     padding: 20px 30px 20px 50px;
}
.factors .text-list ul li:before {
    background-image: url(../img/exclamacao.svg);
}
/*end Section factors*/

/*Section treatment*/
.treatment {
    padding: 90px 0 100px;
}
.treatment .grid {
    gap: 30px;
    align-items: center;
} 
.treatment .grid .grid-img img {
    min-width: 740px;
}
.treatment .grid .grid-item h3 {
    margin-bottom: 20px;
}
.treatment .grid .grid-item ul li {
    padding: 20px 10px 20px 50px;
}
/*end Section treatment*/

/*Section explanation*/
.explanation {
    padding: 80px 0;
}

.explanation h3 {
    max-width: 1145px;
}
.explanation p {
    max-width: 590px;
}
/*end Section explanation*/

/*Section more*/
.more {
    padding: 100px 0;
}
.more h3 {
    max-width: 471px;
}
.more .grid .grid-item .more-btn {
    padding-top: 10px;
    margin-bottom: 30px;
}
.more .grid .grid-item .more-btn a {
    padding: 20px 40px;
    color: var(--color-white);
    font-size: 18px;
    font-weight: bold;
    background-color: var(--color-pink);
    border-radius: 8px;
}
.more .grid .grid-item .small a {
    font-weight: bold;
    color: var(--color-pink);
}
.more.bg-grey .grid {
    grid-template-columns: 60% 1fr;
    align-items: center;
}
/*end Section more*/

/* References*/
.ref {
    padding: 50px 0;
    display: flex;
    justify-content: center;
    align-items: center;
}
.ref p {
    margin-bottom: 10px;
    margin-top: 10px;
}
.ref p:nth-child(2) {
    margin-bottom: 60px;
}
.ref p:nth-child(2), .ref p:nth-child(3) {
    color: #7B818B;
}

/* Responsive */
/* Responsive */
@media (max-width: 1500px) {
    .banner::before {
        width: 1500px;
    }
}
@media (max-width: 1400px) {
    h1 {
        font-size: 50px;
        line-height: 55px;
    }
    .more.bg-grey h3 {
        font-size: 24px;

    }
    .banner::before {
        width: 1420px;
        height: 730px;
    }
    .explanation h3 {
        max-width: 1000px;
    }
    .prevalence-item:nth-child(3) .box {
        padding: 60px 10px 20px 30px;
    }
    .risks hr {
        width: 90%;
        left: 4%;
    }
    .treatment .grid .grid-img img {
        min-width: 100%;
    }
    .more .grid .grid-item .small br {
        display: none;
    }
}
@media (max-width: 1400px) {
    .explanation h3 {
        max-width: 1000px;
    }
}
@media (max-width: 1199px) {
    .banner::before {
        width: 1210px;
        height: 650px;
    }
    h1 {
        font-size: 40px;
        line-height: 45px;
        padding-top: 30px;
    }
    .banner h3 {
        margin-top: 50px;
    }
    .prevalence .prevalence-row {
        grid-template-columns: repeat(3, 1fr);
        column-gap: 20px;
        row-gap: 60px;
    }
    .risks hr {
        width: 95%;
        left: 3%;
    }
    .quality .quality-text br  {
        display: none;
    }
    .signals .grid {
        gap: 50px;
    }
    .more.bg-grey .grid {
        gap: 20px;
    }
}
@media (max-width: 991px) {
    h1 {
        font-size: 32px;
        line-height: 42px;
        padding-top: 20px;
    }
    h2 {
        font-size: 35px;
    }
    h3  {
        font-size: 30px;
        line-height: 35px;
    }
    .grid {
        grid-template-columns: 1fr;
    }
    .banner::before {
        width: 1000px;
        height: 500px;
        top: 0;
    }
    .banner h3 {
        margin-top: 80px;
    }
    .about .about-text .text-list p:first-child {
        max-width: 385px;
    }
    .impact .grid {
        gap: 10px;
    }
    .impact .impact-item {
        width: 100%;
    }
    .impact p {
        max-width: none;
    }
    .prevalence h4 br {
        display: none;
    }
    .risks {
        padding: 90px 0 40px;
    }
    .risks .grid {
        gap: 160px;
    }
    .risks .grid .risks-item, .risks .grid .risks-item:last-child {
        justify-content: center;
    }
    .risks .grid .risks-item img, .risks .grid .risks-item:last-child img {
        left: 50%;
    }
    .quality .grid .quality-text {
        max-width: none;
    }
    .explanation h3 {
        font-size: 28px;
    }
    .explanation br {
        display: none;
    }
    .more {
        padding: 100px 0 50px;
    }
    .more.bg-grey .grid {
        grid-template-columns: 1fr;
        gap: 30px;
    }
    .ref {
        padding: 70px 0;
    }
}
@media (max-width: 768px) {
    h1 {
        font-size: 30px;
        line-height: 40px;
        padding-top: 40px;
    }
    h3 {
        font-size: 28px;
    }
    .banner {
        padding-top: 40px;
        background-color: #fafafa;
    }
    .banner::before {
        display: none;
    }
    .banner h3 {
        margin-top: 40px;
    }
    .grid {
        gap: 30px;
    }
    .about.grid {
        display: block;
    }
    .about .about-image .img img {
        max-width: none;
        height: auto;
    }
    .img {
        width: 100%;
        overflow: auto;
    }
    .img img {  
        max-width: none;
        width: unset;
    }
    .prevalence .prevalence-row {
        grid-template-columns: repeat(2, 1fr);
    }
    .prevalence-item:nth-child(3) .box {
        padding: 60px 10px 20px 20px;
    }
    .quality .grid {
        gap: 30px;
    }
    .warnings .box {
        margin: 20px 0 40px;
    }
    .warnings .box p {
        margin: 0 0 0 40px;
    }
    .factors {
        padding: 30px 0 60px;
    }
    .explanation {
        padding: 80px 0 30px;
    }

    .ref p {
        word-break: break-all;
    }
    .risks hr {
        display: none;
    }
    .quality .grid .quality-image img {
        width: unset;
    }
    .quality .grid {
        display: block;
    }
   
}

@media (max-width: 414px) {
    .container {
        width: 90%;
    }
    .banner{
        background-position: bottom;
    }
    .banner h1 {
        font-size: 25px;
        line-height: 30px;
    }
    h3 {
        font-size: 24px;
        line-height: 32px;
    }
    .banner .text p {
        max-width: 300px;
    }
    .prevalence .prevalence-row {
        grid-template-columns: 1fr;
    }
    .warnings .box {
        margin: 10px 0 20px;
    }
   .signals {
        padding-top: 60px;
   }
   .explanation h3 {
        font-size: 24px;
   }
   
    
}